Fildena 100 mg
Fildena is a loyal, experienced and successful medication that helps to treat male incapacity to have great quality, long lasting intercourse. The great regulation of the drug is attained due to Sildenafil Citrate as an energetic additive.
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Description of Fildena Pills
You can buy from online Fildena 100 mg, 120mg, 150mg, and 200mg. If you are having erectile dysfunction. Basically, it occurs only in men. Here is the solution for you. This medicine is widely used in India. Fortune Health Care manufactures Tablet. This medicine is fully made in India.
Main additive is Sildenafil citrate 100 mg along with magnesium stearate, titanium dioxide, microcrystalline cellulose, and calcium phosphate.
Medicine color- Fildena purple
Now you will have many questions regarding reviewer.
What is Fildena Pill. How these days it works?
Buy Fildena 100 mg medicine contains Sildenafil, which belongs to a group of medicines called specific Phosphodiesterase-5 (PDE5) and is used to treat erectile dysfunction in men and pulmonary arterial hypertension. This medicine is not applicable for women and children below 18 years and people on nitrates like nitroglycerin.
How does Sildenafil work?
It is the generic name for brand medicines. They are PDE5 interceptions, which magnifies nitric oxide exemption, which magnifies blood flow into the penis, so that an erection can be obtained and kept. It merely works when you are induced or aroused. Basically, it lasts in your complex for about five to six hours.
How do you take it?
It comes as a pill. You can take it as required, meaning one hour before the . The main beginning dose is 50 milligrams, although some men necessity is a larger dose of Fildena 100mg Particularly in the case of a taller person. Others can get away with smaller dose of 25mg.
When we should take this medicine?
This medicine should be best taken on an empty stomach.
How well does Sildenafil work?
It is very effective. Its effectiveness in studies has been shown to be 84% on average, which is actually very high for a medication. It means that in the maximum men who have Erectile dysfunction (ED) symptoms. Definitely, they will see an development when having a treatment like Sildenafil.
How long before Sildenafil starts working?
Within 30 minutes, it usually starts working, with its maximum capability at one hour. It lasts in your complex for up to five to six hours.
How many dose can be taken in 24 hours?
Keep in mind that, in 24 hours one dose of Sildenafil should only be taken.
Can I take Sildenafil while I am taking other medicines at the same time?
The interaction of Sildenafil with Angina medicines like nitrate tablets and GTN spray and there is some blood pressure medications such as Doxazocin.
How to use its medicine?
Many times, the doctor recommends that it should be taken 1hr before having. A man can only take one tablet a day. This tablet can be without in taking or with in taking of meal too increases its absorption.
Is it safe to take this medicine?
Yes, there are not any long-term health problems or side effects. It is not recommended for men who have recently had a heart attack or a stroke in the previous six month, who have uncontrolled high blood pressure, severely low blood pressure or unstable Angina symptoms.
What is Erectile Dysfunction?
Erectile Dysfunction is the inability to maintain an erection the causes are clogged blood vessels, high blood pressure, heart disease, obesity, diabetes and metabolic syndrome among others.
What are the risk factors?
Getting older, having a chronic heart condition, medications, smoking, alcohol, abuse obesity and stress. There are several tests that can be done including ultrasound neurological evaluation, psychological evaluation and invasive tests.
Treatment methods are oral medications, needle injection therapy, hormone replacement therapy, penis pumps, vascular surgery, penile implants and psychological counseling. There are several ways to reduce the chances of having erectile dysfunction.
How Sildenafil works in erectile dysfunction?
Erectile tissue is controlled by the autonomic nervous system and parasympathetic system produce erection of the erectile tissue whereas sympathetic is going to produce quite opposite effect, it produces ejaculation.
Now this erection is in vasodilation response that is caused by parasympathetic system and ejaculation is a vasoconstrictor response which is produced by sympathetic system. So here the erection of the erectile tissue is mediated by parasympathetic system by vasodilatation.
How it can produce a vasodilation?
Parasympathetic system is going to act through the cholinergic receptors. These cholinergic receptors release one of the mediator "nitric oxide". Now this nitric oxide is called as non adrenergic non cholinergic (NANC) mediator that means this mediator is neither related to the adrenergic nor cholinergic existence, but it is released by the cholinergic system into endothelium.
Now this nitric oxide which is release into the endothelium then acts on the vascular smooth muscle to produce the vasodilatation.
What is vasodilation?
It is the dilatation of blood pressure, which decreases blood pressure.
What is PDE-5?
It is Phosphodiesterase type- 5 enzyme. It is found in blood vessels walls, from working properly. It helps to control blood flow to the pulmonary arteries.
What is the role of PDE-5 (Phosphodiesterase type-5) enzyme in the erection process?
Corpus cavernous is the major mass of this rigid (erectile) tissue which is in charge of the erection process. Neurons can release the mediator nitric oxide into corpus cavernous when there is a stimulation and endothelium can also release this nitric oxide into the corpus cavernosum. Now this released nitric oxide then stimulates the Gonad cyclase enzyme (GC).
When GC is activated it will convert the GTP into the cyclic GMP. Now, cyclic GMP is one of the important secondary messenger that is released through the stimulation of the nitric oxide. Then this cyclic GMP is going to stimulate Protein kinase G. It can control the calcium permeability into the corpus cavernous.
What is the important messenger in the corpus cavernosum?
The important messenger here is the cyclic GMP which leads to the relaxation of the smooth muscle and can be metabolized the GMP by one of the important enzyme Phosphodiesterase type 5 . This enzyme is more abundant in the corpus cavernosum which is inhibited by one of the drug Sildenafil.
So the Sildenafil inhibits the metabolism of cyclic GMP into the GMP there might increase the cyclic GMP levels within the corpus cavernous. Due to this action of Sildenafil cyclic, GMP levels are going to increase which resists the more relaxation and more erection of the erectile tissue.
So Sildenafil causes the smooth muscle relaxation and increase the blood flow into erectile tissue which results in the direction of the erectile tissue.
What is penile erection?
It is one of the first responses to occur during arousal. It is vascular phenomenon resulting from neutrally mediated increase in blood flow to the penile erection tissue.
What is the mechanism of penile erection?
So, whenever there is a stimulation, it stimulates neurons. These neurons are going to release important mediator nitric oxide. Now this nitric oxide can also be released from the endothelium. We have seen that parasympathetic system release a nitric oxide from the endothelium. Now this nitric oxide is responsible for the penile erection.
This nitric oxide increased the cyclic GMP. Thereby, it acts on the vascular smooth muscles within the erectile tissue which brings the vasodilatation and erection of the erectile tissue.
What if Sildenafil does not work?
Sildenafil might not work for you, if you took two smaller dose, if you were not aroused or if you had it with food. Initially, we recommend to wait a day and try another bigger dose if you were not already on the maximum dose. If not, have a chat to your doctor about other treatment options.
Can women take Sildenafil?
Sorry women, it is not licensed for use in women and studies have shown that it does not work in women. Also, there is some concern about the long term effects, it may have on the female body.
What could be the warning and precautions?
This medicine should not be taken without the prescription of your doctor- If you are suffering with heart problems, low or high blood pressure, severe vision loss, kidney or liver problems, blood problems including sickle cell anemia or leukemia and a deformed painless Peyronie disease. The medicine is not designated for women use.
What are the common side effects?
Most men do not notice side effects. But for those that do, they may get many health issues. With this medication, alcohol consumption is prohibited, as it can make those side effects worse.
Possible side effects when overdose of Fildena 100 mg medicine:
-> Dizziness
-> Indigestion
-> Hypotension
-> Upset stomach
-> Headache
-> Flushing (vasodilator effect)
-> Priapism (pain on erection)
-> Visual changes (not able to discriminate blue and green color)
Tell your doctor if you are taking following medicines such as medicines that contain nitrates and Isosorbide Mononitrate and other medical treatments that erections. Contact if you notice any side effects such as headache, flushing of the face of text stomach and temporary changes in certain degrees or loss of vision. https://en.wikipedia.org/wiki/Pulmonary_hypertension
What are the serious Fildena side effects?
If you get an erection that lasts for longer than four hours, please see a doctor immediately. As it is a medical emergency. Mor dosage Fildena 150 mg , Fildena 200 mg